Replenishment orders should ideally be initiated when inventory levels reach predetermined reorder points, striking a balance between avoiding stockouts and minimizing excess inventory. These reorder points are calculated based on various factors, including lead time, demand variability, safety stock requirements, and desired service levels. By replenishing inventory at the right time, businesses can ensure continuity in supply while optimizing inventory carrying costs. However, determining the ideal moment requires careful consideration of lead times from suppliers, demand patterns, and the cost of holding inventory. Additionally, the use of automated inventory management systems can help streamline the replenishment process by automatically triggering orders when inventory levels hit predefined thresholds, ensuring timely replenishment without the need for manual intervention.